TBCB antibody (AA 1-100) (HRP)

Catalog No. ABIN1410794

The Rabbit Polyclonal anti-TBCB antibody has been validated for WB, ELISA, IHC (p) and IHC (fro). It is suitable to detect TBCB in samples from Human.

Quick Overview for TBCB antibody (AA 1-100) (HRP) (ABIN1410794)

Target: TBCB (Tubulin Folding Cofactor B (TBCB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TBCB antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TBCB Antibody (HRP)

Binding Specificity: AA 1-100

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CKAP1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for TBCB

Target: TBCB (Tubulin Folding Cofactor B (TBCB))

Alternative Name: CKAP1/TBCB

Background:

Synonyms: CG22, CKAPI, Cytoskeleton associated protein 1, Cytoskeleton associated protein CKAPI, Cytoskeleton-associated protein 1, Cytoskeleton-associated protein CKAPI, TBCB, TBCB_HUMAN, Tubulin folding cofactor B, Tubulin specic chaperone B, Tubulin-folding cofactor B, Tubulin-specic chaperone B.

Background: Microtubules, the primary component of the cytoskeletal network, are highly dynamic structures composed of Alpha/Beta Tubulin heterodimers. Biosynthesis of functional microtubules involve the participation of several chaperones, termed Tubulin folding cofactors A (TBCA), B (TBCB), D (TBCD), E (TBCE) and C (TBCC), that act on folding intermediates downstream of the cytosolic chaperon, alternatively named TCP. TBCB (tubulin folding cofactor B), also known as CG22, CKAP1 or CKAPI, is a 244 amino acid cytoplasmic protein containing one CAP-Gly domain and in widely expressed. TBCB is involved in the regulation of tubulin heterodimer dissociation and may function as a negative regulator of axonal growth.